Enhancing the dissolution rate of poorly soluble drug Febuxostat using spray dried amorphous solid dispersion technique

Abstract Introduction: Febuxostat belongs to Biopharmaceutical classification system (BCS) class II drugs, which have low solubility and high permeability.Amorphous solid dispersion is one of the techniques which can be useful to improve solubility and powder characteristics.Objective: To optimize the concentration of hydrophilic and hydrophobic po

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